APOLIPOPROTEINAS A Y B PDFAPOLIPOPROTEINAS A Y B PDF

(Its official name is apolipoprotein B.) Find out in this article. ApoB (the bad protein) and Cholesterol. We all know about the bad cholesterol – LDL. But science is. Cholesterol-rich, apolipoprotein B (apoB)-containing lipoproteins are now widely accepted as the most important causal agents of. The APOB gene provides instructions for making two versions of the apolipoprotein B protein, a short version called apolipoprotein B and a longer version.

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Systems used to automatically annotate proteins with high accuracy:. Select item s and click on “Add to basket” to create your own collection here entries max.

Manual assertion based on experiment in i.

Manual assertion according to rules i. Manual assertion inferred from combination of experimental and computational evidence i.

Comprehensive resource for the study of protein post-translational modifications PTMs in human, mouse and rat. The displayed sequence is further processed into a mature form. This entry has 1 described isoform and 1 potential isoform that is computationally mapped.

APOB – Apolipoprotein B precursor – Homo sapiens (Human) – APOB gene & protein

Show all Align All. You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser. Your basket is currently empty. Reviewed – Annotation score: Select a section on the left to see content. Apolipoprotein B Short name: HPA Endoplasmic reticulum endoplasmic reticulum exit site Source: Reactome endoplasmic reticulum membrane Source: Reactome smooth endoplasmic reticulum Source: Reactome Endosome early endosome Source: Reactome endosome lumen Source: Reactome endosome membrane Source: Reactome Extracellular region or secreted chylomicron Source: Ensembl intermediate-density lipoprotein particle Source: Reactome Plasma Membrane plasma membrane Source: Reactome Other locations clathrin-coated endocytic vesicle membrane Source: Reactome intracellular membrane-bounded organelle Source: HPA neuronal cell body Source: The disease is caused by mutations affecting the gene represented in this entry.

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Disease description A disorder of lipid metabolism characterized by less than 5th percentile age- and sex-specific levels of low density lipoproteins, and dietary fat malabsorption.

Apolipoprotein B-100

Clinical presentation may vary from no symptoms to severe gastrointestinal and neurological dysfunction similar to abetalipoproteinemia. Identification of a new mutation that decreases LDL receptor binding affinity.

Disease description Dominantly inherited disorder of lipoprotein metabolism leading to hypercholesterolemia and increased proneness to coronary artery disease CAD. Defects in APOB associated with defects in other genes polygenic can contribute to hypocholesterolemia. IIMonroe M. Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle. Non-supervised Orthologous Groups More Eukaryotic Ortholog Groups More It is useful for tracking sequence updates.

The algorithm is described in the ISO standard. The sequence AAA differs from that shown.

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Frameshift apolipoprtoeinas positions,and Edited at position Apo B, derived from the fully edited RNA, is produced only in the intestine and is found in chylomicrons. Evidence for more than one gene per haploid genome. These are stable identifiers and should be used to cite UniProtKB entries. P Secondary accession number s: National Institutes of U.

Do not show this banner again. Cholesterol metabolismLipid metabolismLipid transportSteroid metabolismSterol metabolismTransport.

Reactome – a knowledgebase of biological pathways and processes More Apo B Cleaved into the following chain: Four distinct tokens exist: It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.

Eukaryotic Pathogen Database Resources More Human Gene Apolipoproteinax Database More Corresponds to variant dbSNP: Does not affect protein secretion. GeneReviews a resource of expert-authored, peer-reviewed disease descriptions.

MalaCards human disease database More Orphanet; a database dedicated to information on rare diseases and orphan drugs More BioMuta curated single-nucleotide variation and disease association database More S-palmitoyl cysteine 1 Publication Manual assertion based on experiment in i Ref. Phosphoserine Combined sources Manual assertion inferred from combination of experimental aplipoproteinas computational evidence i Ref.

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Phosphothreonine Combined sources Manual assertion inferred from combination of experimental and computational evidence i Ref. Encyclopedia of Proteome Dynamics More PaxDb, a database of protein abundance averages across all three domains of life More ProteomicsDB human proteome resource More CarbonylDB database of protein carbonylation sites More GlyConnect protein glycosylation platform More SwissPalm database of S-palmitoylation events More UniCarbKB; an annotated and curated apollpoproteinas of glycan structures More ENSG Expressed in 86 apolipkproteinas shighest expression level in jejunal mucosa.

Apolipoprotein B-containing lipoproteins and atherosclerotic cardiovascular disease

P baseline and differential. Genevisible search portal to normalized and curated expression data from Genevestigator More Human Protein Atlas More Database of interacting proteins More Protein interaction database and analysis system More Molecular INTeraction database More BindingDB database of measured binding affinities More Database of comparative protein structure models More Database of Orthologous Groups More Database for complete collections of gene phylogenies More TreeFam database of animal gene trees More Integrated resource of protein families, domains and functional sites More Pfam protein domain database More Superfamily database of structural and functional annotation More Apolipoprotein B Apolipoprotein B These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples.

Sequence conflicts are usually of unknown origin. Missing 1 Publication Manual assertion based on experiment in i Ref. Select the link destinations: EMBL nucleotide sequence database More Protein sequence database of the Protein Information Resource More UniGene gene-oriented nucleotide sequence clusters More Ensembl eukaryotic genome annotation project More Kyoto Encyclopedia of Genes and Genomes More UCSC genome browser More Apolipoprotein B gene intron CI and flanking regions Fragment.

Apolipoprotein B gene intron Bi and flanking regions Fragment.